Dr Brian Tyson

Brian Tyson is a board certified family physician in El Centro, California. California physician Brian Tyson successfully treated thousands of patients with hydroxychloroquine in his clinic. In the studio of One America News , he said he has now cured nearly 5,000 patients. Two patients died and six had to go to hospital. The doctor also warned that an experimental vaccine puts people at risk unnecessarily. When asked how this personal HCQ involvement began for him, Dr Tyson tells a tragic story of how his daughter’s music manager went to…

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Dr. Vladimir Zelenko

(Sadly, Dr Zelenko passed away in June 2022 after a long fight with cancer. An obituary is here) Interviewed on the Highwire by Del Bigtree 3 July 2020 {https://thehighwire.com/} Dr. Zelenko comes on about 42 mins in. (Prior interviewees: John Ziegler, Senior columnist; Reinette Senum, Mayor Nevada City, CA) Approximate transcript (may be incomplete at the beginning) Referring to Didier Raoult’s work and others…they were doing it in the lab or patients in the hospital. My patients were outpatients. The best solution to the respiratory crisis is to prevent people…

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Country-level comparisons

In the early part of the pandemic, many people charted the emerging picture of high Covid-19 death rates in developed countries with a large pharmaceutical industry presence (whose governments generally opposed HCQ) and low rates in poorer countries (that already used HCQ or were quick to adopt it). This resulted in a number of comparative analyses. Summary (i) An analysis by the group Americas Frontline Doctors by country, showed that access to HCQ was strongly linked to lower Covid-19 mortality. (ii) A worldwide country comparison generated automatically by the website…

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14 statistically significant

Lead author     Improvement   RR       [CI]     Outcome         Treatment        Control            Dose (4d) Gautret                      66%     0.34 [0.17-0.68] viral+            6/20                 14/16               2.4g Esper                           64%     0.36 [0.15-0.87] hosp.           8/412               12/224             2.0 Huang (ES)                 59%     0.41 [0.26-0.66] viral time     32/32               37/37              2.0g (c) Chen (RCT)                72%     0.28 [0.10-0.82] viral time     18/18               12/12              1.6g Hong                           65%     0.35 [0.13-0.72] viral+            42/42               48/48               n/a Bernabeu-Wittel          59%     0.41 [0.36-0.95] death           189 (n)             83 (n)               2.0g Ly                                56%     0.44 [0.26-0.75] death           18/116             29/110             2.4g Heras                           96%     0.04 [0.02-0.09] death            8/70                 16/30               n/a Sulaiman                     64%     0.36 [0.17-0.80] death            7/1,817           54/3,724          2.0g Szente Fonseca          …

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Accinelli – completing the picture

As noted, 30+ other studies strongly indicate the merits of treating Covid-19 early with Hydroxychloroquine. One notable study not on the list provides quantification and important wider context. Accinelli et al, Hydroxychloroquine / azithromycin in COVID-19: The association between time to treatment and case fatality rate https://www.sciencedirect.com/science/article/pii/S1477893921002040 Summary of importance The Accinelli study has relevance as yet another basic hydroxychloroquine Covid-19 early treatment study. So why is it not on the list? It’s because everyone in the study received HCQ. It has much wider relevance because it studied the effect…

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Some Main Studies

Virtually all of the 31/32 studies of early treatment using hydroxychlorquine had positive primary outcomes. In a sign test, if in reality HCQ had no benefit, the odds this happening is billions to one against. 14 of the outcomes were statistically significant. Here are some of those studies, borrowing from the useful descriptions of c19study.com: Sulaiman et al. “This observational prospective cohort study took place in 238 ambulatory fever clinics in Saudi Arabia, which followed the Ministry of Health (MOH) COVID-19 treatment guideline. This guideline included multiple treatment options for…

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