14 statistically significant

Lead author     Improvement   RR       [CI]     Outcome         Treatment        Control            Dose (4d) Gautret                      66%     0.34 [0.17-0.68] viral+            6/20                 14/16               2.4g Esper                           64%     0.36 [0.15-0.87] hosp.           8/412               12/224             2.0 Huang (ES)                 59%     0.41 [0.26-0.66] viral time     32/32               37/37              2.0g (c) Chen (RCT)                72%     0.28 [0.10-0.82] viral time     18/18               12/12              1.6g Hong                           65%     0.35 [0.13-0.72] viral+            42/42               48/48               n/a Bernabeu-Wittel          59%     0.41 [0.36-0.95] death           189 (n)             83 (n)               2.0g Ly                                56%     0.44 [0.26-0.75] death           18/116             29/110             2.4g Heras                           96%     0.04 [0.02-0.09] death            8/70                 16/30               n/a Sulaiman                     64%     0.36 [0.17-0.80] death            7/1,817           54/3,724          2.0g Szente Fonseca          …

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Accinelli – completing the picture

As noted, 30+ other studies strongly indicate the merits of treating Covid-19 early with Hydroxychloroquine. One notable study not on the list provides quantification and important wider context. Accinelli et al, Hydroxychloroquine / azithromycin in COVID-19: The association between time to treatment and case fatality rate https://www.sciencedirect.com/science/article/pii/S1477893921002040 Summary of importance The Accinelli study has relevance as yet another basic hydroxychloroquine Covid-19 early treatment study. So why is it not on the list? It’s because everyone in the study received HCQ. It has much wider relevance because it studied the effect…

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